Association of cytochrome P450 genetic polymorphisms with neoadjuvant chemotherapy efficacy in breast cancer patients

BACKGROUND: The enzymes of the cytochrome P450 family (CYPs) play an important role in the metabolism of a great variety of anticancer agents; therefore, polymorphisms in genes encoding for metabolizing enzymes and drugs transporters can affect drug efficacy and toxicity. METHODS: The genetic polymo...

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Bibliografiske detaljer
Main Authors: Seredina, Tatyana A, Goreva, Olga B, Talaban, Valeria O, Grishanova, Alevtina Yu, Lyakhovich, Vyacheslav V
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458973/
https://ncbi.nlm.nih.gov/pubmed/22702493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-13-45
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