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Dioxin (TCDD) Induces Epigenetic Transgenerational Inheritance of Adult Onset Disease and Sperm Epimutations

Environmental compounds can promote epigenetic transgenerational inheritance of adult-onset disease in subsequent generations following ancestral exposure during fetal gonadal sex determination. The current study examined the ability of dioxin (2,3,7,8-tetrachlorodibenzo[p]dioxin, TCDD) to promote e...

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Detalhes bibliográficos
Main Authors: Manikkam, Mohan, Tracey, Rebecca, Guerrero-Bosagna, Carlos, Skinner, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458876/
https://ncbi.nlm.nih.gov/pubmed/23049995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046249
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