Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion.

A conformational change in the hemagglutinin glycoprotein of influenza virus has been observed to occur to pH values corresponding to those optimal for the membrane fusion activity of the virus. CD, electron microscopic, and sedimentation analyses show that, in the pH range 5.2-4.9, bromelain-solubi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Skehel, J J, Bayley, P M, Brown, E B, Martin, S R, Waterfield, M D, White, J M, Wilson, I A, Wiley, D C
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1982
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345880/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6951181/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.4.968
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