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Synthesis of chiral sulfoximine-based thioureas and their application in asymmetric organocatalysis

For the first time, chiral sulfoximine derivatives have been applied as asymmetric organocatalysts. In combination with a thiourea-type backbone the sulfonimidoyl moiety leads to organocatalysts showing good reactivity in the catalytic desymmetrization of a cyclic meso-anhydride and moderate enantio...

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Detalhes bibliográficos
Main Authors: Frings, Marcus, Thomé, Isabelle, Bolm, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458769/
https://ncbi.nlm.nih.gov/pubmed/23019479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.164
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