Exploring chemical diversity via a modular reaction pairing strategy

The efficient synthesis of an 80-member library of unique benzoxathiazocine 1,1-dioxides by a microwave-assisted, intermolecular nucleophilic aromatic substitution (S(N)Ar) diversification pathway is reported. Eight benzofused sultam cores were generated by means of a sulfonylation/S(N)Ar/Mitsunobu...

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Hlavní autoři: Loh, Joanna K, Yoon, Sun Young, Samarakoon, Thiwanka B, Rolfe, Alan, Porubsky, Patrick, Neuenswander, Benjamin, Lushington, Gerald H, Hanson, Paul R
Médium: Artigo
Jazyk:Inglês
Vydáno: Beilstein-Institut 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458752/
https://ncbi.nlm.nih.gov/pubmed/23019462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.147
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