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Functional Characterization of the Stringent Response Regulatory Gene dksA of Vibrio cholerae and Its Role in Modulation of Virulence Phenotypes

In bacteria, nutrient deprivation evokes the stringent response, which is mediated by the small intracellular signaling molecule ppGpp. In Gram negatives, the RelA enzyme synthesizes and SpoT hydrolyzes ppGpp, although the latter protein also has weak synthetase activity. DksA, a recently identified...

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Detalhes bibliográficos
Main Authors: Pal, Ritesh Ranjan, Bag, Satyabrata, Dasgupta, Shreya, Das, Bhabatosh, Bhadra, Rupak K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458680/
https://ncbi.nlm.nih.gov/pubmed/22904284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00518-12
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