Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes

Despite the promise of RNA interference (RNAi) and its potential, e.g. for use in cancer therapy, several technical obstacles must first be overcome. The major hurdle of RNAi-based therapeutics is to deliver nucleic acids across the cell’s plasma membrane. This study demonstrates that exosome vesicl...

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Bibliografische gegevens
Hoofdauteurs: Wahlgren, Jessica, Karlson, Tanya De L., Brisslert, Mikael, Vaziri Sani, Forugh, Telemo, Esbjörn, Sunnerhagen, Per, Valadi, Hadi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2012
Onderwerpen:
Methods Online
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458529/
https://ncbi.nlm.nih.gov/pubmed/22618874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks463
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