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Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes

Despite the promise of RNA interference (RNAi) and its potential, e.g. for use in cancer therapy, several technical obstacles must first be overcome. The major hurdle of RNAi-based therapeutics is to deliver nucleic acids across the cell’s plasma membrane. This study demonstrates that exosome vesicl...

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Detalhes bibliográficos
Main Authors: Wahlgren, Jessica, Karlson, Tanya De L., Brisslert, Mikael, Vaziri Sani, Forugh, Telemo, Esbjörn, Sunnerhagen, Per, Valadi, Hadi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458529/
https://ncbi.nlm.nih.gov/pubmed/22618874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks463
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