Absence of MyD88 Signaling Induces Donor-Specific Kidney Allograft Tolerance

Toll-like receptors (TLRs) play a fundamental role in innate immunity and provide a link between innate and adaptive responses to an allograft; however, whether the development of acute and chronic allograft rejection requires TLR signaling is unknown. Here, we studied TLR signaling in a fully MHC-m...

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Hlavní autoři: Wu, Huiling, Noordmans, Gerda A., O’Brien, Maya R., Ma, Jin, Zhao, Cathy Y., Zhang, Geoff Y., Kwan, Tony K.T., Alexander, Stephen I., Chadban, Steven J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2012
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458459/
https://ncbi.nlm.nih.gov/pubmed/22878960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012010052
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