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Wnt ligands signal in a cooperative manner to promote foregut organogenesis

Endoderm-mesenchyme cross-talk is a central process in the development of foregut-derived organs. How signaling pathways integrate the activity of multiple ligands to guide organ development is poorly understood. We show that two Wnt ligands, Wnt2 and Wnt7b, cooperatively induce Wnt signaling withou...

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Détails bibliographiques
Auteurs principaux: Miller, Mayumi F., Cohen, Ethan David, Baggs, Julie E., Lu, Min Min, Hogenesch, John B., Morrisey, Edward E.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458331/
https://ncbi.nlm.nih.gov/pubmed/22949635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201583109
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