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Rational Development of a Cytotoxic Peptide to Trigger Cell Death

Defects in the apoptotic machinery can contribute to tumor formation and resistance to treatment, creating a need to identify new agents that kill cancer cells by alternative mechanisms. To this end, we examined the cytotoxic properties of a novel peptide, CT20p, derived from the C-terminal, alpha-9...

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Detalhes bibliográficos
Main Authors: Boohaker, Rebecca J., Zhang, Ge, Lee, Michael W., Nemec, Kathleen N., Santra, Santimukul, Perez, J. Manuel, Khaled, Annette R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458162/
https://ncbi.nlm.nih.gov/pubmed/22591113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300167e
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