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Environmental and pharmacological modulation of cellular plasticity: role in the pathophysiology and treatment of depression

Atrophy of neurons and gross structural alterations of limbic brain regions, including the prefrontal cortex (PFC) and hippocampus, have been reported in brain imaging and postmortem studies of depressed patients. Preclinical findings have suggested that prolonged negative stress can induce changes...

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Detalhes bibliográficos
Main Authors: Ota, Kristie T., Duman, Ronald S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458126/
https://ncbi.nlm.nih.gov/pubmed/22691453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.05.022
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