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The p50 Subunit of NF-κB Orchestrates Dendritic Cell Lifespan and Activation of Adaptive Immunity

Dendritic cells play a central role in keeping the balance between immunity and immune tolerance. A key factor in this equilibrium is the lifespan of DC, as its reduction restrains antigen availability leading to termination of immune responses. Here we show that lipopolysaccharide-driven DC maturat...

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Detalhes bibliográficos
Main Authors: Larghi, Paola, Porta, Chiara, Riboldi, Elena, Totaro, Maria Grazia, Carraro, Lorenzo, Orabona, Ciriana, Sica, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458114/
https://ncbi.nlm.nih.gov/pubmed/23049782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045279
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