Proteome Analysis Identified the PPARγ Ligand 15d-PGJ2 as a Novel Drug Inhibiting Melanoma Progression and Interfering with Tumor-Stroma Interaction

Peroxisome proliferator-activated receptors (PPARs) have been originally thought to be restricted to lipid metabolism or glucose homeostasis. Recently, evidence is growing that PPARγ ligands have inhibitory effects on tumor growth. To shed light on the potential therapeutic effects on melanoma we te...

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Autores principales: Paulitschke, Verena, Gruber, Silke, Hofstätter, Elisabeth, Haudek-Prinz, Verena, Klepeisz, Philipp, Schicher, Nikolaus, Jonak, Constanze, Petzelbauer, Peter, Pehamberger, Hubert, Gerner, Christopher, Kunstfeld, Rainer
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458105/
https://ncbi.nlm.nih.gov/pubmed/23049949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046103
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