Store-Operated Ca(2+) Entry Is Remodelled and Controls In Vitro Angiogenesis in Endothelial Progenitor Cells Isolated from Tumoral Patients

BACKGROUND: Endothelial progenitor cells (EPCs) may be recruited from bone marrow to sustain tumor vascularisation and promote the metastatic switch. Understanding the molecular mechanisms driving EPC proliferation and tubulogenesis could outline novel targets for alternative anti-angiogenic treatme...

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Hauptverfasser: Lodola, Francesco, Laforenza, Umberto, Bonetti, Elisa, Lim, Dmitry, Dragoni, Silvia, Bottino, Cinzia, Ong, Hwei Ling, Guerra, Germano, Ganini, Carlo, Massa, Margherita, Manzoni, Mariangela, Ambudkar, Indu S., Genazzani, Armando A., Rosti, Vittorio, Pedrazzoli, Paolo, Tanzi, Franco, Moccia, Francesco, Porta, Camillo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458053/
https://ncbi.nlm.nih.gov/pubmed/23049731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042541
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