Local Delivery of Nimodipine by Prolonged-Release Microparticles—Feasibility, Effectiveness and Dose-Finding in Experimental Subarachnoid Hemorrhage

BACKGROUND AND PURPOSE: To investigate the effect of locally applied nimodipine prolonged-release microparticles on angiographic vasospasm and secondary brain injury after experimental subarachnoid hemorrhage (SAH). METHODS: 70 male Wistar rats were categorized into three groups: 1) sham operated an...

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Detalhes bibliográficos
Main Authors: Hänggi, Daniel, Perrin, Jason, Eicker, Sven, Beseoglu, Kerim, Etminan, Nima, Kamp, Marcel Alexander, Heiroth, Hi-Jae, Bege, Nadia, Macht, Stephan, Frauenknecht, Katrin, Sommer, Clemens, Kissel, Thomas, Steiger, Hans-Jakob
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458040/
https://ncbi.nlm.nih.gov/pubmed/23049732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042597
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