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Resting-State Network Disruption and APOE Genotype in Alzheimer's Disease: A lagged Functional Connectivity Study

BACKGROUND: The apolipoprotein E epsilon 4 (APOE-4) is associated with a genetic vulnerability to Alzheimer's disease (AD) and with AD-related abnormalities in cortical rhythms. However, it is unclear whether APOE-4 is linked to a specific pattern of intrinsic functional disintegration of the b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Canuet, Leonides, Tellado, Ivan, Couceiro, Veronica, Fraile, Carmen, Fernandez-Novoa, Lucia, Ishii, Ryouhei, Takeda, Masatoshi, Cacabelos, Ramon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457973/
https://ncbi.nlm.nih.gov/pubmed/23050006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046289
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