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Low-Dose Dextromethorphan, a NADPH Oxidase Inhibitor, Reduces Blood Pressure and Enhances Vascular Protection in Experimental Hypertension

BACKGROUND: Vascular oxidative stress may be increased with age and aggravate endothelial dysfunction and vascular injury in hypertension. This study aimed to investigate the effects of dextromethorphan (DM), a NADPH oxidase inhibitor, either alone or in combination treatment, on blood pressure (BP)...

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Autors principals: Wu, Tao-Cheng, Chao, Chih-Yu, Lin, Shing-Jong, Chen, Jaw-Wen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457948/
https://ncbi.nlm.nih.gov/pubmed/23049937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046067
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