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Drugs Which Inhibit Osteoclast Function Suppress Tumor Growth through Calcium Reduction in Bone

Prostate carcinoma frequently metastasizes to bone where the microenvironment facilitates its growth. Inhibition of bone resorption is effective in reducing tumor burden and bone destruction in prostate cancer. However, whether drugs that inhibit osteoclast function inhibit tumor growth independent...

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Detalhes bibliográficos
Main Authors: Li, Xin, Liao, Jinhui, Park, Serk In, Koh, Amy J, Sadler, William D, Pienta, Kenneth J, Rosol, Thomas J, McCauley, Laurie K
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457787/
https://ncbi.nlm.nih.gov/pubmed/21419883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2011.03.687
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