Drugs Which Inhibit Osteoclast Function Suppress Tumor Growth through Calcium Reduction in Bone

Prostate carcinoma frequently metastasizes to bone where the microenvironment facilitates its growth. Inhibition of bone resorption is effective in reducing tumor burden and bone destruction in prostate cancer. However, whether drugs that inhibit osteoclast function inhibit tumor growth independent...

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Bibliografiske detaljer
Main Authors: Li, Xin, Liao, Jinhui, Park, Serk In, Koh, Amy J, Sadler, William D, Pienta, Kenneth J, Rosol, Thomas J, McCauley, Laurie K
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457787/
https://ncbi.nlm.nih.gov/pubmed/21419883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2011.03.687
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