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A Model for the Evolution of the Mammalian T-cell Receptor α/δ and μ Loci Based on Evidence from the Duckbill Platypus

The specific recognition of antigen by T cells is critical to the generation of adaptive immune responses in vertebrates. T cells recognize antigen using a somatically diversified T-cell receptor (TCR). All jawed vertebrates use four TCR chains called α, β, γ, and δ, which are expressed as either a...

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Main Authors: Parra, Zuly E., Lillie, Mette, Miller, Robert D.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457774/
https://ncbi.nlm.nih.gov/pubmed/22593227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mss128
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