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Simulated annealing reveals the kinetic activity of SGLT1, a member of the LeuT structural family
The Na(+)/glucose cotransporter (SGLT1) is the archetype of membrane proteins that use the electrochemical Na(+) gradient to drive uphill transport of a substrate. The crystal structure recently obtained for vSGLT strongly suggests that SGLT1 adopts the inverted repeat fold of the LeuT structural fa...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3457693/ https://ncbi.nlm.nih.gov/pubmed/23008432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210822 |
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