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Denosumab: a new option in the treatment of bone metastases from urological cancers

Bone metastases often create serious clinical problems: they lead to poor performance status due to pathologic fractures, spinal cord compression and intractable pain, commonly referred to as skeletal-related events. The receptor activator of nuclear factor-κB (RANK), the RANK ligand (RANKL), and os...

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Main Authors: Yuasa, Takeshi, Yamamoto, Shinya, Urakami, Shinji, Fukui, Iwao, Yonese, Junji
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457675/
https://ncbi.nlm.nih.gov/pubmed/23055747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S30578
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