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Oncogenic activation of c-Abl in non-small cell lung cancer cells lacking FUS1 expression: inhibition of c-Abl by the tumor suppressor gene product Fus1

In lung cancer, frequent loss of one allele of chromosome 3p is seen in both small cell lung cancer and non-small cell lung cancer (NSCLC), providing evidence of tumor suppressor genes (TSGs) in this chromosomal region. The mechanism of Fus1 tumor suppressor activity is unknown. We have found that a...

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Detalhes bibliográficos
Main Authors: Lin, J, Sun, T, Ji, L, Deng, W, Roth, J, Minna, J, Arlinghaus, R
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457636/
https://ncbi.nlm.nih.gov/pubmed/17486070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210500
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