The WalKR System Controls Major Staphylococcal Virulence Genes and Is Involved in Triggering the Host Inflammatory Response

The WalKR two-component system is essential for the viability of Staphylococcus aureus, playing a central role in controlling cell wall metabolism. We produced a constitutively active form of WalR in S. aureus through a phosphomimetic amino acid replacement (WalR(c), D55E). The strain displayed sign...

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Main Authors: Delauné, Aurélia, Dubrac, Sarah, Blanchet, Charlène, Poupel, Olivier, Mäder, Ulrike, Hiron, Aurélia, Leduc, Aurélie, Fitting, Catherine, Nicolas, Pierre, Cavaillon, Jean-Marc, Adib-Conquy, Minou, Msadek, Tarek
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Host Response and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457574/
https://ncbi.nlm.nih.gov/pubmed/22825451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00195-12
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