The K1K2 Region of Lys-Gingipain of Porphyromonas gingivalis Blocks Induction of HLA Expression by Gamma Interferon

In the context of periodontal disease, cysteine proteinases or gingipains from Porphyromonas gingivalis have been implicated in the hydrolysis of cytokines, including gamma interferon (IFN-γ). This cytokine plays a crucial role in host defenses, in part, by regulating expression of major histocompat...

Full description

Saved in:
Bibliographic Details
Main Authors: Yun, Peter L., Li, Nan, Collyer, Charles A., Hunter, Neil
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457573/
https://ncbi.nlm.nih.gov/pubmed/22802347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00528-12
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items