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Abscess Formation and Alpha-Hemolysin Induced Toxicity in a Mouse Model of Staphylococcus aureus Peritoneal Infection

Staphylococcus aureus is a frequent cause of skin infection and sepsis in humans. Preclinical vaccine studies with S. aureus have used a mouse model with intraperitoneal challenge and survival determination as a measure for efficacy. To appreciate the selection of protective antigens in this model,...

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Bibliografiske detaljer
Main Authors: Rauch, Sabine, DeDent, Andrea C., Kim, Hwan Keun, Bubeck Wardenburg, Juliane, Missiakas, Dominique M., Schneewind, Olaf
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457571/
https://ncbi.nlm.nih.gov/pubmed/22802349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00442-12
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