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Evidence for insulin-induced internalization and degradation of insulin receptors in rat adipocytes.
We have investigated the theory that the insulin-induced loss of insulin binding from adipocytes is due to internalization of insulin receptors. Cell-surface receptors were assessed by the binding capacity of intact cells at 16 degrees C. Total (i.e., cell-surface plus intracellular) receptors were...
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Autori principali: | , |
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Natura: | Artigo |
Lingua: | Inglês |
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1982
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC345756/ https://ncbi.nlm.nih.gov/pubmed/7043460 |
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