Evidence for insulin-induced internalization and degradation of insulin receptors in rat adipocytes.
We have investigated the theory that the insulin-induced loss of insulin binding from adipocytes is due to internalization of insulin receptors. Cell-surface receptors were assessed by the binding capacity of intact cells at 16 degrees C. Total (i.e., cell-surface plus intracellular) receptors were...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1982
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7043460/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.2.427 |
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