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Evidence for insulin-induced internalization and degradation of insulin receptors in rat adipocytes.
We have investigated the theory that the insulin-induced loss of insulin binding from adipocytes is due to internalization of insulin receptors. Cell-surface receptors were assessed by the binding capacity of intact cells at 16 degrees C. Total (i.e., cell-surface plus intracellular) receptors were...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
1982
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC345756/ https://ncbi.nlm.nih.gov/pubmed/7043460 |
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