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Evidence for insulin-induced internalization and degradation of insulin receptors in rat adipocytes.

We have investigated the theory that the insulin-induced loss of insulin binding from adipocytes is due to internalization of insulin receptors. Cell-surface receptors were assessed by the binding capacity of intact cells at 16 degrees C. Total (i.e., cell-surface plus intracellular) receptors were...

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Detalles Bibliográficos
Main Authors: Green, A, Olefsky, J M
Formato: Artigo
Idioma:Inglês
Publicado: 1982
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC345756/
https://ncbi.nlm.nih.gov/pubmed/7043460
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