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FHL2 Binds Calcineurin and Represses Pathological Cardiac Growth

Stress-induced hypertrophic growth of the heart predisposes the heart to arrhythmia, contractile dysfunction, and clinical heart failure. FHL2 (four-and-a-half LIM domain protein 2) is expressed predominantly in the heart, and inactivation of the gene coding for FHL2 leads to exaggerated responsiven...

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Autori principali: Hojayev, Berdymammet, Rothermel, Beverly A., Gillette, Thomas G., Hill, Joseph A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457523/
https://ncbi.nlm.nih.gov/pubmed/22851699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05948-11
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