Requirement of Signal Peptidase ComC and Thiol-Disulfide Oxidoreductase DsbA for Optimal Cell Surface Display of Pseudopilin ComGC in Staphylococcus aureus

Staphylococcus aureus is an important Gram-positive bacterial pathogen producing many secreted and cell surface-localized virulence factors. Here we report that the staphylococcal thiol-disulfide oxidoreductase DsbA is essential for stable biogenesis of the ComGC pseudopilin. The signal peptidase Co...

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Main Authors: van der Kooi-Pol, Magdalena M., Reilman, Ewoud, Sibbald, Mark J. J. B., Veenstra-Kyuchukova, Yanka K., Kouwen, Thijs R. H. M., Buist, Girbe, van Dijl, Jan Maarten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Genetics and Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457507/
https://ncbi.nlm.nih.gov/pubmed/22820325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01565-12
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