The Liver Partition Coefficient-Corrected Inhibitory Quotient and the Pharmacokinetic-Pharmacodynamic Relationship of Directly Acting Anti-Hepatitis C Virus Agents in Humans

Pharmacokinetic-pharmacodynamic (PK-PD) data analyses from early hepatitis C virus (HCV) clinical trials failed to show a good correlation between the plasma inhibitory quotient (IQ) and antiviral activity of different classes of directly acting antiviral agents (DAAs). The present study explored wh...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Duan, Jianmin, Bolger, Gordon, Garneau, Michel, Amad, Ma'an, Batonga, Joëlle, Montpetit, Hélène, Otis, François, Jutras, Martin, Lapeyre, Nicole, Rhéaume, Manon, Kukolj, George, White, Peter W., Bethell, Richard C., Cordingley, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457380/
https://ncbi.nlm.nih.gov/pubmed/22869578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01028-12
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados