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Characterization of Resistance to the Protease Inhibitor GS-9451 in Hepatitis C Virus-Infected Patients

GS-9451, a novel hepatitis C virus (HCV) nonstructural 3/4a (NS3/4a) protease inhibitor, is highly active in patients infected with HCV genotype 1 (GT 1). The aim of this study is to characterize the clinical resistance profile of GS-9451 in GT 1 HCV-infected patients in a phase 1, 3-day monotherapy...

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Bibliografiset tiedot
Päätekijät: Dvory-Sobol, Hadas, Wong, Kelly A., Ku, Karin S., Bae, Andrew, Lawitz, Eric J., Pang, Phillip S., Harris, Jeanette, Miller, Michael D., Mo, Hongmei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457362/
https://ncbi.nlm.nih.gov/pubmed/22869562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00780-12
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