Myd88-Dependent Toll-Like Receptor 7 Signaling Mediates Protection from Severe Ross River Virus-Induced Disease in Mice

Arthralgia-associated alphaviruses, including chikungunya virus (CHIKV) and Ross River virus (RRV), pose significant public health threats because of their ability to cause explosive outbreaks of debilitating arthralgia and myalgia in human populations. Although the host inflammatory response is kno...

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Main Authors: Neighbours, Lauren M., Long, Kristin, Whitmore, Alan C., Heise, Mark T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457316/
https://ncbi.nlm.nih.gov/pubmed/22837203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00601-12
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