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5′-Triphosphate-Short Interfering RNA: Potent Inhibition of Influenza A Virus Infection by Gene Silencing and RIG-I Activation

Limited protection of current vaccines and antiviral drugs against influenza A virus infection underscores the urgent need for development of novel anti-influenza virus interventions. While short interfering RNA (siRNA) has been shown to be able to inhibit influenza virus infection in a gene-specifi...

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Detalles Bibliográficos
Main Authors: Lin, Li, Liu, Qiang, Berube, Nathalie, Detmer, Susan, Zhou, Yan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457308/
https://ncbi.nlm.nih.gov/pubmed/22787226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00665-12
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