The Attenuated Genotype of Varicella-Zoster Virus Includes an ORF0 Transitional Stop Codon Mutation

Varicella-zoster virus (VZV) is the first of the human herpesviruses to be attenuated and subsequently approved as a live vaccine to prevent varicella and herpes zoster. Both the attenuated VZV vaccine, called vaccine Oka or vOka, and the parental strain pOka have been completely sequenced. Yet the...

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Detalhes bibliográficos
Main Authors: Peters, Geoffrey A., Tyler, Shaun D., Carpenter, John E., Jackson, Wallen, Mori, Yasuko, Arvin, Ann M., Grose, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457260/
https://ncbi.nlm.nih.gov/pubmed/22837206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01067-12
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