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Three Murine Leukemia Virus Integration Regions within 100 Kilobases Upstream of c-myb Are Proximal to the 5′ Regulatory Region of the Gene through DNA Looping

Retroviruses integrated into genomic DNA participate in long-range gene activation from as far away as several hundred kilobases. Hypotheses have been put forth to account for these phenomena, but data have not been provided to support a physical mechanism that explains long-range activation. In mur...

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Autors principals: Zhang, Junfang, Markus, Jan, Bies, Juraj, Paul, Thomas, Wolff, Linda
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457256/
https://ncbi.nlm.nih.gov/pubmed/22811527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01077-12
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