Early HLA-B*57-Restricted CD8(+) T Lymphocyte Responses Predict HIV-1 Disease Progression

Although HLA-B*57 (B57) is associated with slow progression to disease following HIV-1 infection, B57 heterozygotes display a wide spectrum of outcomes, including rapid progression, viremic slow progression, and elite control. Efforts to identify differences between B57-positive (B57(+)) slow progre...

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Autori principali: Brennan, Catherine A., Ibarrondo, F. Javier, Sugar, Catherine A., Hausner, Mary Ann, Shih, Roger, Ng, Hwee L., Detels, Roger, Margolick, Joseph B., Rinaldo, Charles R., Phair, John, Jacobson, Lisa P., Yang, Otto O., Jamieson, Beth D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457253/
https://ncbi.nlm.nih.gov/pubmed/22811521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00102-12
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