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Membrane Disruption by Antimicrobial Fatty Acids Releases Low-Molecular-Weight Proteins from Staphylococcus aureus

The skin represents an important barrier for pathogens and is known to produce fatty acids that are toxic toward Gram-positive bacteria. A screen of fatty acids as growth inhibitors of Staphylococcus aureus revealed structure-specific antibacterial activity. Fatty acids like oleate (18:1Δ9) were non...

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Bibliografiske detaljer
Main Authors: Parsons, Joshua B., Yao, Jiangwei, Frank, Matthew W., Jackson, Pamela, Rock, Charles O.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457211/
https://ncbi.nlm.nih.gov/pubmed/22843840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00743-12
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