Memory CD4(+) T Lymphocytes in the Gastrointestinal Tract Are a Major Source of Cell-Associated Simian Immunodeficiency Virus in Chronic Nonpathogenic Infection of African Green Monkeys

Simian immunodeficiency virus (SIV) infection of natural hosts is characterized by nonpathogenic chronic viremia, maintenance of gastrointestinal epithelial barrier integrity, and low numbers of target cells. Assessment of cell-associated virus load in T cell subsets in multiple anatomic compartment...

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Detalhes bibliográficos
Main Authors: Schmitz, Joern E., Ma, Zhong-Min, Hagan, Emily A., Wilks, Andrew B., Furr, Kathryn L., Linde, Caitlyn H., Zahn, Roland C., Brenchley, Jason M., Miller, Christopher J., Permar, Sallie R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457182/
https://ncbi.nlm.nih.gov/pubmed/22896600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01556-12
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