Epstein-Barr Virus Transcription Activator R Upregulates BARF1 Expression by Direct Binding to Its Promoter, Independent of Methylation

Epstein-Barr virus (EBV) BamHI-A rightward frame 1 (BARF1) is considered a major viral oncogene in epithelial cells and has immune-modulating properties. However, in B cells and lymphomas, BARF1 expression is restricted to the viral lytic replication cycle. In this report, the transcriptional regula...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Hoebe, E. K., Wille, C., Hopmans, E. S., Robinson, A. R., Middeldorp, J. M., Kenney, S. C., Greijer, A. E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457140/
https://ncbi.nlm.nih.gov/pubmed/22896599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01161-12
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky