Acute Cytomegalovirus Infection Is Associated with Increased Frequencies of Activated and Apoptosis-Vulnerable T Cells in HIV-1-Infected Infants

Cytomegalovirus (CMV) coinfection is associated with infant HIV-1 disease progression and mortality. In a cohort of Kenyan HIV-infected infants, the frequencies of activated (CD38(+) HLA-DR(+)) and apoptosis-vulnerable (CD95(+) Bcl-2(−)) CD4(+) and CD8(+) T cells increased substantially during acute...

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Detalhes bibliográficos
Main Authors: Slyker, Jennifer A., Rowland-Jones, Sarah L., Dong, Tao, Reilly, Marie, Richardson, Barbra, Emery, Vincent C., Atzberger, Ann, Mbori-Ngacha, Dorothy, Lohman-Payne, Barbara L., John-Stewart, Grace C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457128/
https://ncbi.nlm.nih.gov/pubmed/22875969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00790-12
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