Blockade of the brain histamine H3 receptor by JNJ-39220675: preclinical PET studies with [(11)C]GSK189254 in anesthetized baboon

RATIONALE: The preclinical characterization of a series of aryloxypyridine amides has identified JNJ-39220675 ((4-cyclobutyl-1,4-diazepan-1-yl)(6-(4-fluorophenoxy)pyridin-3-yl)methanone) as a high-affinity histamine H(3) receptor antagonist and a candidate for further drug development particularly i...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Logan, Jean, Carruthers, Nicholas I., Letavic, Michael A., Sands, Steven, Jiang, Xiaohui, Shea, Colleen, Muench, Lisa, Xu, Youwen, Carter, Pauline, King, Payton, Fowler, Joanna S.
格式: Artigo
語言:Inglês
出版: Springer-Verlag 2012
主題:
Original Investigation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3456925/
https://ncbi.nlm.nih.gov/pubmed/22614669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-012-2733-x
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍