Blockade of the brain histamine H3 receptor by JNJ-39220675: preclinical PET studies with [(11)C]GSK189254 in anesthetized baboon

RATIONALE: The preclinical characterization of a series of aryloxypyridine amides has identified JNJ-39220675 ((4-cyclobutyl-1,4-diazepan-1-yl)(6-(4-fluorophenoxy)pyridin-3-yl)methanone) as a high-affinity histamine H(3) receptor antagonist and a candidate for further drug development particularly i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Logan, Jean, Carruthers, Nicholas I., Letavic, Michael A., Sands, Steven, Jiang, Xiaohui, Shea, Colleen, Muench, Lisa, Xu, Youwen, Carter, Pauline, King, Payton, Fowler, Joanna S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer-Verlag 2012
Gaiak:
Original Investigation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3456925/
https://ncbi.nlm.nih.gov/pubmed/22614669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-012-2733-x
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak