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Isolation of enterotoxin structural gene deletion mutations in Vibrio cholerae induced by two mutagenic vibriophages.

Phenotypically nontoxinogenic mutants of Vibrio cholerae were isolated after infection with either of two mutagenic vibriophages, VcAI and VcA2ctsl. DNA isolated from these mutants was analyzed for toxin gene sequences by the Southern blotting method with 32P-labeled probes derived from the cloned A...

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Main Authors: Mekalanos, J J, Moseley, S L, Murphy, J R, Falkow, S
Format: Artigo
Sprog:Inglês
Udgivet: 1982
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC345680/
https://ncbi.nlm.nih.gov/pubmed/6948297
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