A beta-globin gene, inactive in the K562 leukemic cell, functions normally in a heterologous expression system.

The K562 human leukemia cell is an erythroid-like cell that may serve as a model for the study of globin gene expression in transcriptionally active human erythroid cells. K562 cells express all globin genes with the exception of that for beta-globin; failure to produce beta-globin could result from...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Fordis, C M, Anagnou, N P, Dean, A, Nienhuis, A W, Schechter, A N
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1984
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345615/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6205398/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.14.4485
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