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Patterns of metabolic activity during aging of the wild type and longevity mutants of Caenorhabditis elegans
At least three mechanisms determine life span in Caenorhabditis elegans. An insulin-like signaling pathway regulates dauer diapause, reproduction and longevity. Reduction-or loss-of-function mutations in this pathway can extend longevity substantially, suggesting that the wild-type alleles shorten l...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Kluwer Academic Publishers
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3455783/ https://ncbi.nlm.nih.gov/pubmed/23604840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-000-0007-8 |
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