Patient-Specific Probes for Preimplantation Genetic Diagnosis of Structural and Numerical Aberrations in Interphase Cells

Purpose:Our purpose was to evaluate the utility of translocation breakpoint-spanning DNA probes for prenatal genetic diagnosis of structural and numerical chromosome aberrations in interphase cells. Methods:Breakpoint-spanning translocation probes were isolated from large insert DNA libraries and la...

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Main Authors: Weier, Heinz-Ulli G., Munné, Santiago, Fung, Jingly
Format: Artigo
Jezik:Inglês
Izdano: Kluwer Academic Publishers-Plenum Publishers 1999
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455766/
https://ncbi.nlm.nih.gov/pubmed/10224561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1020360706317
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