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Isolation, primary structure, and synthesis of human hypothalamic somatocrinin: growth hormone-releasing factor.

The hypophysiotropic peptide, growth hormone-releasing factor (GRF), was isolated from human hypothalamic-hypophysial tissues by means of acid extraction, immunoaffinity chromatography, gel filtration, and two steps of reverse-phase high-performance liquid chromatography. Amino acid sequence determi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ling, N, Esch, F, Böhlen, P, Brazeau, P, Wehrenberg, W B, Guillemin, R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345576/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6431406/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.14.4302
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