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Evidence of extrachromosomal forms of hepatitis B viral DNA in a bone marrow culture obtained from a patient recently infected with hepatitis B virus.

A cell culture that produces Dane-like particles was initiated from a bone marrow aspirate of an acute hepatitis B patient. By using Southern blot analysis and a recombinant hepatitis B virus (HBV) DNA plasmid probe, extrachromosomal forms of HBV DNA were detected. The two forms of HBV DNA migrate a...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Elfassi, E, Romet-Lemonne, J L, Essex, M, Frances-McLane, M, Haseltine, W A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1984
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345541/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6587366/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.11.3526
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