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Life span extensions associated with upregulation of gene expression of antioxidant enzymes in Caenorhabdms elegans; studies of mutation in the AGE-1, PI3 kinase homologue and short-term exposure to hyperoxia
Life span could be modified by genetic or environmental perturbations in Caenorhabditis elegans. Here we show that two extensions of life span are associated with oxidative stress resistance and upregulation of the gene expression of antioxidant enzymes. First, mutations in age-1 gene (PI3 kinase ho...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Kluwer Academic Publishers
2001
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3455294/ https://ncbi.nlm.nih.gov/pubmed/23604883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-001-0019-z |
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